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A human mutation in Phox2b causes lack of CO(2) chemosensitivity, fatal central apnea, and specific loss of parafacial neurons

Breathing is maintained and controlled by a network of neurons in the brainstem that generate respiratory rhythm and provide regulatory input. Central chemoreception, the mechanism for CO(2) detection that provides an essential stimulatory input, is thought to involve neurons located near the medull...

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Bibliografiske detaljer
Main Authors: Dubreuil, Véronique, Ramanantsoa, Nélina, Trochet, Delphine, Vaubourg, Vanessa, Amiel, Jeanne, Gallego, Jorge, Brunet, Jean-François, Goridis, Christo
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2242699/
https://ncbi.nlm.nih.gov/pubmed/18198276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0709115105
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