Unlicensed NK cells target neuroblastoma following anti-GD2 antibody treatment

Survival outcomes for patients with high-risk neuroblastoma (NB) have significantly improved with anti-disialoganglioside GD2 mAb therapy, which promotes NK cell activation through antibody-dependent cell-mediated cytotoxicity. NK cell activation requires an interaction between inhibitory killer cel...

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Detalhes bibliográficos
Main Authors: Tarek, Nidale, Le Luduec, Jean-Benoit, Gallagher, Meighan M., Zheng, Junting, Venstrom, Jeffrey M., Chamberlain, Elizabeth, Modak, Shakeel, Heller, Glenn, Dupont, Bo, Cheung, Nai-Kong V., Hsu, Katharine C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2012
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3428088/
https://ncbi.nlm.nih.gov/pubmed/22863621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI62749
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