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INSULIN CONTROLS THE SPATIAL DISTRIBUTION OF GLUT4 ON THE CELL SURFACE THROUGH REGULATION OF ITS POST-FUSION DISPERSAL
While the glucose transporter-4 (GLUT4) is fundamental to insulin-regulated glucose metabolism, its dynamic spatial organization in the plasma membrane (PM) is unclear. Here, using multi-color TIRF microscopy in transfected adipose cells, we demonstrate that insulin regulates not only the exocytosis...
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| Main Authors: | , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2010
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3427691/ https://ncbi.nlm.nih.gov/pubmed/20816091 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2010.08.005 |
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