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Insulin Regulates Fusion of GLUT4 Vesicles Independent of Exo70-mediated Tethering

Insulin regulates cellular glucose uptake by changing the amount of glucose transporter-4 (GLUT4) in the plasma membrane through stimulation of GLUT4 exocytosis. However, how the particular trafficking, tethering, and fusion steps are regulated by insulin is still debated. In a 3T3-L1 adipocyte cell...

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Autors principals: Lizunov, Vladimir A., Lisinski, Ivonne, Stenkula, Karin, Zimmerberg, Joshua, Cushman, Samuel W.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2658084/
https://ncbi.nlm.nih.gov/pubmed/19155211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M806460200
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