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Insulin stimulates the halting, tethering, and fusion of mobile GLUT4 vesicles in rat adipose cells

Glucose transport in adipose cells is regulated by changing the distribution of glucose transporter 4 (GLUT4) between the cell interior and the plasma membrane (PM). Insulin shifts this distribution by augmenting the rate of exocytosis of specialized GLUT4 vesicles. We applied time-lapse total inter...

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Main Authors: Lizunov, Vladimir A., Matsumoto, Hideko, Zimmerberg, Joshua, Cushman, Samuel W., Frolov, Vadim A.
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2005
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2171949/
https://ncbi.nlm.nih.gov/pubmed/15866888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200412069
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