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Insulin-containing lipogenic stimuli suppress mast cell degranulation potential and up-regulate lipid body biogenesis and eicosanoid secretion in a PPARγ-independent manner

Lipid bodies are most studied in adipocytes, where the lipogenic action of insulin initiates their formation. Here, we test the hypothesis that insulin may regulate lipid body content in mast cells and hence, modify their proinflammatory potential. Our data show that insulin causes lipid body accumu...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Greineisen, William E., Shimoda, Lori M. N., Maaetoft-Udsen, Kristina, Turner, Helen
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Society for Leukocyte Biology 2012
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3427608/
https://ncbi.nlm.nih.gov/pubmed/22706316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0811406
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