Transcriptional and Functional Plasticity Induced by Chronic Insulin Exposure in a Mast Cell-Like Basophilic Leukemia Cell Model

OBJECTIVE: Secretory granules (SG) and lipid bodies (LB) are the primary organelles that mediate functional responses in mast cells. SG contains histamine and matrix-active proteases, while LB are reservoirs of arachidonic acid and its metabolites, precursors for rapid synthesis of eicosanoids such...

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Detalhes bibliográficos
Publicado no:J Immunobiol
Main Authors: Jansen, Chad, Speck, Mark, Greineisen, William E, Maaetoft-Udsen, Kristina, Cordasco, Edward, Shimoda, Lori MN, Stokes, Alexander J, Turner, Helen
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5804893/
https://ncbi.nlm.nih.gov/pubmed/29430572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4172/2476-1966.1000135
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