Rac-Induced Left Ventricular Dilation in Thyroxin-Treated ZmRacD Transgenic Mice: Role of Cardiomyocyte Apoptosis and Myocardial Fibrosis

The pathways inducing the critical transition from compensated hypertrophy to cardiac dilation and failure remain poorly understood. The goal of our study is to determine the role of Rac-induced signaling in this transition process. Our previous results showed that Thyroxin (T4) treatment resulted i...

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Detalhes bibliográficos
Main Authors: Elnakish, Mohammad T., Hassona, Mohamed D. H., Alhaj, Mazin A., Moldovan, Leni, Janssen, Paul M. L., Khan, Mahmood, Hassanain, Hamdy H.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3427332/
https://ncbi.nlm.nih.gov/pubmed/22936985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0042500
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