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Rac1 Is Required for Cardiomyocyte Apoptosis During Hyperglycemia

OBJECTIVE: Hyperglycemia induces reactive oxygen species (ROS) and apoptosis in cardiomyocytes, which contributes to diabetic cardiomyopathy. The present study was to investigate the role of Rac1 in ROS production and cardiomyocyte apoptosis during hyperglycemia. RESEARCH DESIGN AND METHODS: Mice wi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Shen, E., Li, Yanwen, Li, Ying, Shan, Limei, Zhu, Huaqing, Feng, Qingping, Arnold, J. Malcolm O., Peng, Tianqing
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Diabetes Association 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2750234/
https://ncbi.nlm.nih.gov/pubmed/19592621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db08-0617
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