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Rac1 Signaling Is Critical to Cardiomyocyte Polarity and Embryonic Heart Development

BACKGROUND: Defects in cardiac septation are the most common form of congenital heart disease, but the mechanisms underlying these defects are still poorly understood. The small GTPase Rac1 is implicated in planar cell polarity of epithelial cells in Drosophila; however, its role in mammalian cardio...

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Bibliografske podrobnosti
izdano v:J Am Heart Assoc
Main Authors: Leung, Carmen, Lu, Xiangru, Liu, Murong, Feng, Qingping
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Publishing Ltd 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4323834/
https://ncbi.nlm.nih.gov/pubmed/25315346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.114.001271
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