Rac1 Signaling Is Required for Anterior Second Heart Field Cellular Organization and Cardiac Outflow Tract Development

BACKGROUND: The small GTPase Rac1 regulates diverse cellular functions, including both apicobasal and planar cell polarity pathways; however, its role in cardiac outflow tract (OFT) development remains unknown. In the present study, we aimed to examine the role of Rac1 in the anterior second heart f...

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Bibliografiske detaljer
Udgivet i:J Am Heart Assoc
Main Authors: Leung, Carmen, Liu, Yin, Lu, Xiangru, Kim, Mella, Drysdale, Thomas A., Feng, Qingping
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2015
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4859369/
https://ncbi.nlm.nih.gov/pubmed/26722124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.115.002508
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