Rac1 Is Required for Cardiomyocyte Apoptosis During Hyperglycemia

OBJECTIVE: Hyperglycemia induces reactive oxygen species (ROS) and apoptosis in cardiomyocytes, which contributes to diabetic cardiomyopathy. The present study was to investigate the role of Rac1 in ROS production and cardiomyocyte apoptosis during hyperglycemia. RESEARCH DESIGN AND METHODS: Mice wi...

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Autors principals: Shen, E., Li, Yanwen, Li, Ying, Shan, Limei, Zhu, Huaqing, Feng, Qingping, Arnold, J. Malcolm O., Peng, Tianqing
Format: Artigo
Idioma:Inglês
Publicat: American Diabetes Association 2009
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2750234/
https://ncbi.nlm.nih.gov/pubmed/19592621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db08-0617
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