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Chronic coexistence of two troponin T isoforms in adult transgenic mouse cardiomyocytes decreased contractile kinetics and caused dilatative remodeling

Our previous in vivo and ex vivo studies suggested that coexistence of two or more troponin T (TnT) isoforms in adult cardiac muscle decreased cardiac function and efficiency (Huang QQ, Feng HZ, Liu J, Du J, Stull LB, Moravec CS, Huang X, Jin JP, Am J Physiol Cell Physiol 294: C213–C22, 2008; Feng H...

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Detalhes bibliográficos
Main Authors: Yu, Zhi-Bin, Wei, Hongguang, Jin, J.-P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3404524/
https://ncbi.nlm.nih.gov/pubmed/22538236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00026.2012
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