The B-MYB Transcriptional Network Guides Cell Cycle Progression and Fate Decisions to Sustain Self-Renewal and the Identity of Pluripotent Stem Cells

Embryonic stem cells (ESCs) are pluripotent and have unlimited self-renewal capacity. Although pluripotency and differentiation have been examined extensively, the mechanisms responsible for self-renewal are poorly understood and are believed to involve an unusual cell cycle, epigenetic regulators a...

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Main Authors: Zhan, Ming, Riordon, Daniel R., Yan, Bin, Tarasova, Yelena S., Bruweleit, Sarah, Tarasov, Kirill V., Li, Ronald A., Wersto, Robert P., Boheler, Kenneth R.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3427317/
https://ncbi.nlm.nih.gov/pubmed/22936984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0042350
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