B-MYB Is Essential for Normal Cell Cycle Progression and Chromosomal Stability of Embryonic Stem Cells

BACKGROUND: The transcription factor B-Myb is present in all proliferating cells, and in mice engineered to remove this gene, embryos die in utero just after implantation due to inner cell mass defects. This lethal phenotype has generally been attributed to a proliferation defect in the cell cycle p...

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Detalhes bibliográficos
Main Authors: Tarasov, Kirill V., Tarasova, Yelena S., Tam, Wai Leong, Riordon, Daniel R., Elliott, Steven T., Kania, Gabriela, Li, Jinliang, Yamanaka, Satoshi, Crider, David G., Testa, Gianluca, Li, Ronald A., Lim, Bing, Stewart, Colin L., Liu, Yie, Van Eyk, Jennifer E., Wersto, Robert P., Wobus, Anna M., Boheler, Kenneth R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2423619/
https://ncbi.nlm.nih.gov/pubmed/18575582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0002478
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