B-MYB Is Essential for Normal Cell Cycle Progression and Chromosomal Stability of Embryonic Stem Cells

BACKGROUND: The transcription factor B-Myb is present in all proliferating cells, and in mice engineered to remove this gene, embryos die in utero just after implantation due to inner cell mass defects. This lethal phenotype has generally been attributed to a proliferation defect in the cell cycle p...

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Библиографические подробности
Главные авторы: Tarasov, Kirill V., Tarasova, Yelena S., Tam, Wai Leong, Riordon, Daniel R., Elliott, Steven T., Kania, Gabriela, Li, Jinliang, Yamanaka, Satoshi, Crider, David G., Testa, Gianluca, Li, Ronald A., Lim, Bing, Stewart, Colin L., Liu, Yie, Van Eyk, Jennifer E., Wersto, Robert P., Wobus, Anna M., Boheler, Kenneth R.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2008
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2423619/
https://ncbi.nlm.nih.gov/pubmed/18575582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0002478
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