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Investigating cellular identity and manipulating cell fate using induced pluripotent stem cells

Induced pluripotent stem (iPS) cells, obtained from reprogramming somatic cells by ectopic expression of a defined set of transcription factors or chemicals, are expected to be used as differentiated cells for drug screening or evaluations of drug toxicity and cell replacement therapies. As pluripot...

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Detalhes bibliográficos
Main Authors: Sugawara, Tohru, Nishino, Koichiro, Umezawa, Akihiro, Akutsu, Hidenori
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3392777/
https://ncbi.nlm.nih.gov/pubmed/22405125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/scrt99
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