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IgG1(+) ovalbumin-specific B-cell transnuclear mice show class switch recombination in rare allelically included B cells
We used somatic cell nuclear transfer (SCNT) to generate a mouse from the nucleus of an IgG1(+) ovalbumin-specific B cell. The resulting OBI mice show generally normal B-cell development, with elevated percentages of marginal zone B cells and a reduction in B-1 B cells. Whereas OBI RAG1(−/−) mice ha...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3427072/ https://ncbi.nlm.nih.gov/pubmed/22869725 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1210273109 |
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