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Oncolytic virus-mediated tumor radiosensitization in mice through DNA-PKcs-specific shRNA

One of the key issues in cancer radiotherapy research is to sensitize tumor cells to the cell killing effects of ionizing radiation while leaving normal tissues intact. One potential approach to achieve this is through tumor-specific targeting of DNA repair genes. In this study, we engineered a repl...

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Библиографические подробности
Главные авторы: Kon, Takashi, Zhang, Xiuwu, Huang, Qian, Yang, Zhonghui, Liu, Shanling, Yan, Bin, Li, Fang, Wang, He, Li, Chuan-Yuan
Формат: Artigo
Язык:Inglês
Опубликовано: 2012
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3426860/
https://ncbi.nlm.nih.gov/pubmed/22924158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3978/j.issn.2218-676X.2012.05.02
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