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Oncolytic virus-mediated tumor radiosensitization in mice through DNA-PKcs-specific shRNA

One of the key issues in cancer radiotherapy research is to sensitize tumor cells to the cell killing effects of ionizing radiation while leaving normal tissues intact. One potential approach to achieve this is through tumor-specific targeting of DNA repair genes. In this study, we engineered a repl...

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Detalhes bibliográficos
Main Authors: Kon, Takashi, Zhang, Xiuwu, Huang, Qian, Yang, Zhonghui, Liu, Shanling, Yan, Bin, Li, Fang, Wang, He, Li, Chuan-Yuan
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3426860/
https://ncbi.nlm.nih.gov/pubmed/22924158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3978/j.issn.2218-676X.2012.05.02
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