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DNA double-strand breaks and alkali-labile bonds produced by bleomycin.

Both in linear T2 DNA, analyyzed by velocity sedimentation, and in supercoiled Col EL DNA, analyzed by gel electrophoresis, the number of double-strand breaks produced by bleomycin was directly propotional to the number of single-strand breaks and was far greater than the number expected from random...

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Bibliographic Details
Main Authors: Povirk, L F, Wübter, W, Köhnlein, W, Hutchinson, F
Format: Artigo
Language:Inglês
Published: 1977
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC342673/
https://ncbi.nlm.nih.gov/pubmed/73164
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