Chemical Genetics Reveals a Specific Requirement for Cdk2 Activity in the DNA Damage Response and Identifies Nbs1 as a Cdk2 Substrate in Human Cells

The cyclin-dependent kinases (CDKs) that promote cell-cycle progression are targets for negative regulation by signals from damaged or unreplicated DNA, but also play active roles in response to DNA lesions. The requirement for activity in the face of DNA damage implies that there are mechanisms to...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Wohlbold, Lara, Merrick, Karl A., De, Saurav, Amat, Ramon, Kim, Jun Hyun, Larochelle, Stéphane, Allen, Jasmina J., Zhang, Chao, Shokat, Kevan M., Petrini, John H. J., Fisher, Robert P.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2012
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3426557/
https://ncbi.nlm.nih.gov/pubmed/22927831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002935
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak