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Fertility and Pregnancy-Associated ß-Cell Proliferation in Mice Deficient in Proglucagon-Derived Peptides

Proglucagon, which is encoded by the glucagon gene (Gcg), is the precursor of several peptide hormones, including glucagon and glucagon-like peptide 1 (GLP-1). Whereas glucagon stimulates hepatic glycogenolysis and gluconeogenesis, GLP-1 stimulates insulin secretion to lower blood glucose and also s...

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Detalhes bibliográficos
Main Authors: Sugiyama, Chisato, Yamamoto, Michiyo, Kotani, Tomomi, Kikkawa, Fumitaka, Murata, Yoshiharu, Hayashi, Yoshitaka
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3426535/
https://ncbi.nlm.nih.gov/pubmed/22928026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043745
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