Remodeling of Hepatic Metabolism and Hyperaminoacidemia in Mice Deficient in Proglucagon-Derived Peptides

Glucagon is believed to be one of the most important peptides for upregulating blood glucose levels. However, homozygous glucagon–green fluorescent protein (gfp) knock-in mice (Gcg(gfp/gfp): GCGKO) are normoglycemic despite the absence of proglucagon-derived peptides, including glucagon. To characte...

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Hlavní autoři: Watanabe, Chika, Seino, Yusuke, Miyahira, Hiroki, Yamamoto, Michiyo, Fukami, Ayako, Ozaki, Nobuaki, Takagishi, Yoshiko, Sato, Jun, Fukuwatari, Tsutomu, Shibata, Katsumi, Oiso, Yutaka, Murata, Yoshiharu, Hayashi, Yoshitaka
Médium: Artigo
Jazyk:Inglês
Vydáno: American Diabetes Association 2012
Témata:
Metabolism
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3237648/
https://ncbi.nlm.nih.gov/pubmed/22187375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db11-0739
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