The effects of serum lipids on the in vitro activity of lumefantrine and atovaquone against Plasmodium falciparum

BACKGROUND: Lumefantrine and atovaquone are highly lipophilic anti-malarial drugs. As a consequence absorption is increased when the drugs are taken together with a fatty meal, but the free fraction of active drug decreases in the presence of triglyceride-rich plasma lipoproteins. In this study, the...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Chotivanich, Kesinee, Mungthin, Mathirut, Ruengweerayuth, Ronnatrai, Udomsangpetch, Rachanee, Dondorp, Arjen M, Singhasivanon, Pratap, Pukrittayakamee, Sasithon, White, Nicholas J
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2012
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3426466/
https://ncbi.nlm.nih.gov/pubmed/22640826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-11-177
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars