Effects of sevuparin on rosette formation and cytoadherence of Plasmodium falciparum infected erythrocytes

In severe falciparum malaria cytoadherence of parasitised red blood cells (PRBCs) to vascular endothelium (causing sequestration) and to uninfected red cells (causing rosette formation) contribute to microcirculatory flow obstruction in vital organs. Heparin can reverse the underlying ligand-recepto...

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Publicado en:PLoS One
Main Authors: Saiwaew, Somporn, Sritabal, Juntima, Piaraksa, Nattaporn, Keayarsa, Srisuda, Ruengweerayut, Ronnatrai, Utaisin, Chirapong, Sila, Patima, Niramis, Rangsan, Udomsangpetch, Rachanee, Charunwatthana, Prakaykaew, Pongponratn, Emsri, Pukrittayakamee, Sasithon, Leitgeb, Anna M., Wahlgren, Mats, Lee, Sue J., Day, Nicholas P. J., White, Nicholas J., Dondorp, Arjen M., Chotivanich, Kesinee
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2017
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5332063/
https://ncbi.nlm.nih.gov/pubmed/28249043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0172718
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