Effects of sevuparin on rosette formation and cytoadherence of Plasmodium falciparum infected erythrocytes

In severe falciparum malaria cytoadherence of parasitised red blood cells (PRBCs) to vascular endothelium (causing sequestration) and to uninfected red cells (causing rosette formation) contribute to microcirculatory flow obstruction in vital organs. Heparin can reverse the underlying ligand-recepto...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Saiwaew, Somporn, Sritabal, Juntima, Piaraksa, Nattaporn, Keayarsa, Srisuda, Ruengweerayut, Ronnatrai, Utaisin, Chirapong, Sila, Patima, Niramis, Rangsan, Udomsangpetch, Rachanee, Charunwatthana, Prakaykaew, Pongponratn, Emsri, Pukrittayakamee, Sasithon, Leitgeb, Anna M., Wahlgren, Mats, Lee, Sue J., Day, Nicholas P. J., White, Nicholas J., Dondorp, Arjen M., Chotivanich, Kesinee
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5332063/
https://ncbi.nlm.nih.gov/pubmed/28249043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0172718
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