The effects of serum lipids on the in vitro activity of lumefantrine and atovaquone against Plasmodium falciparum

BACKGROUND: Lumefantrine and atovaquone are highly lipophilic anti-malarial drugs. As a consequence absorption is increased when the drugs are taken together with a fatty meal, but the free fraction of active drug decreases in the presence of triglyceride-rich plasma lipoproteins. In this study, the...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Chotivanich, Kesinee, Mungthin, Mathirut, Ruengweerayuth, Ronnatrai, Udomsangpetch, Rachanee, Dondorp, Arjen M, Singhasivanon, Pratap, Pukrittayakamee, Sasithon, White, Nicholas J
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3426466/
https://ncbi.nlm.nih.gov/pubmed/22640826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-11-177
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados