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Fully functionalized small-molecule probes for integrated phenotypic screening and target identification
Phenotypic screening offers a powerful approach to identify small-molecules that perturb complex biological processes in cells and organisms. The tendency of small molecules, however, to interact with multiple protein targets, often with moderate to weak affinities, along with the lack of straightfo...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3426452/ https://ncbi.nlm.nih.gov/pubmed/22667687 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja304213w |
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