Identification of Small Molecule Inhibitors of Pseudomonas aeruginosa Exoenzyme S Using a Yeast Phenotypic Screen

Pseudomonas aeruginosa is an opportunistic human pathogen that is a key factor in the mortality of cystic fibrosis patients, and infection represents an increased threat for human health worldwide. Because resistance of Pseudomonas aeruginosa to antibiotics is increasing, new inhibitors of pharmacol...

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Detalhes bibliográficos
Main Authors: Arnoldo, Anthony, Curak, Jasna, Kittanakom, Saranya, Chevelev, Igor, Lee, Vincent T., Sahebol-Amri, Mehdi, Koscik, Becky, Ljuma, Lana, Roy, Peter J., Bedalov, Antonio, Giaever, Guri, Nislow, Corey, Merrill, Rod A., Lory, Stephen, Stagljar, Igor
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2265467/
https://ncbi.nlm.nih.gov/pubmed/18454192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000005
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