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B-1 cells in the bone marrow are a significant source of natural IgM
Natural IgM antibodies secreted in the absence of antigenic challenge are important contributors to antimicrobial immunity and tissue homeostasis. Early studies had identified bone marrow and, to a lesser extent the spleen, as main tissue sources of this spontaneously secreted IgM. However, the resp...
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| Main Authors: | , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2011
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3426357/ https://ncbi.nlm.nih.gov/pubmed/22009734 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201141890 |
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