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A rapid and convenient synthesis of poly-thymidylic acid by the modified triester approach.

By using anhydrous triethylamine-pyridine to selectively remove the cyanoethyl group from the fully protected oligonucleotide, a substantial improvement has been achieved in yields and the rates of condensation by the modified triester approach from the 5' leads to 3' end. The unreacted ol...

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Dades bibliogràfiques
Publicat a:Nucleic Acids Res
Autors principals: Sood, A K, Narang, S A
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 1977
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC342606/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/909791/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/4.8.2757
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