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The isopropoxyacetic group for convenient base protection during solid-support synthesis of oligodeoxyribonucleotides and their triester analogs.

Isopropoxyacetic anhydride was successfully used for protection of exoaminofunctions of 2'-deoxyadenosine, -guanosine and -cytidine. N-isopropoxyacetylated nucleosides are stable under the conditions of the synthesis of oligodeoxyribonucleotides on the solid support. Removal of N-isopropoxyacet...

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Bibliografische gegevens
Hoofdauteurs: Uznanski, B, Grajkowski, A, Wilk, A
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1989
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC318037/
https://ncbi.nlm.nih.gov/pubmed/2748339
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