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Rapid synthesis of oligodeoxyribonucleotides VII. Solid phase synthesis of oligodeoxyribonucleotides by a continuous flow phosphotriester method on a kieselguhr-polyamide support

A new kieselguhr-polydimethylacrylamide support has been used in a continuous flow, column system for solid phase synthesis of oligodeoxyribonucleotides by a phosphotriester procedure. Using only protected mononucleotides a 14-mer, 20-mer and 27-mer were assembled in high repetitive yield using a si...

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Detalhes bibliográficos
Main Authors: Gait, Michael J., Matthes, Hans W.D., Singh, Mohinder, Sproat, Brian S., Titmas, Richard C.
Formato: Artigo
Idioma:Inglês
Publicado em: 1982
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC326914/
https://ncbi.nlm.nih.gov/pubmed/7177846
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