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Class IA Phosphatidylinositol 3-Kinase p110α Regulates Phagosome Maturation

Of the various phosphatidylinositol 3- kinases (PI3Ks), only the class III enzyme Vps34 has been shown to regulate phagosome maturation. During studies of phagosome maturation in THP-1 cells deficient in class IA PI3K p110α, we discovered that this PI3K isoform is required for vacuole maturation to...

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Bibliografiske detaljer
Main Authors: Thi, Emily P., Lambertz, Ulrike, Reiner, Neil E.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3425514/
https://ncbi.nlm.nih.gov/pubmed/22928013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043668
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