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Engineering synthetic TAL effectors with orthogonal target sites

The ability to engineer biological circuits that process and respond to complex cellular signals has the potential to impact many areas of biology and medicine. Transcriptional activator-like effectors (TALEs) have emerged as an attractive component for engineering these circuits, as TALEs can be de...

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Autori principali: Garg, Abhishek, Lohmueller, Jason J., Silver, Pamela A., Armel, Thomas Z.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3424557/
https://ncbi.nlm.nih.gov/pubmed/22581776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks404
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