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Anti-Peptidoglycan Antibodies and Fcγ Receptors Are the Key Mediators of Inflammation in Gram-Positive Sepsis

Gram-positive bacteria are an important public health problem, but it is unclear how they cause systemic inflammation in sepsis. Our previous work showed that peptidoglycan (PGN) induced proinflammatory cytokines in human cells by binding to an unknown extracellular receptor, followed by phagocytosi...

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Detalhes bibliográficos
Main Authors: Sun, Dawei, Raisley, Brent, Langer, Marybeth, Iyer, Janaki K., Vedham, Vidya, Ballard, Jimmy L., James, Judith A., Metcalf, Jordan, Coggeshall, K. Mark
Formato: Artigo
Idioma:Inglês
Publicado em: AAI 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3424298/
https://ncbi.nlm.nih.gov/pubmed/22815288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1201302
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