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Inflammatory Cytokine Response to Bacillus anthracis Peptidoglycan Requires Phagocytosis and Lysosomal Trafficking

During advanced stages of inhalation anthrax, Bacillus anthracis accumulates at high levels in the bloodstream of the infected host. This bacteremia leads to sepsis during late-stage anthrax; however, the mechanisms through which B. anthracis-derived factors contribute to the pathology of infected h...

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Detalhes bibliográficos
Main Authors: Iyer, Janaki K., Khurana, Taruna, Langer, Marybeth, West, Christopher M., Ballard, Jimmy D., Metcalf, Jordan P., Merkel, Tod J., Coggeshall, K. Mark
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2876538/
https://ncbi.nlm.nih.gov/pubmed/20308305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00170-10
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