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Primary innate immune cells respond efficiently to polymeric peptidoglycan but not to peptidoglycan monomers

The cell wall of bacteria induces pro-inflammatory cytokines in monocytes and neutrophils in human blood. The nature of the stimulating component of bacterial cell walls is not well understood. We have previously shown polymeric peptidoglycan (PGN) has this activity, and the cytokine response requir...

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Autori principali: Iyer, Janaki K., Coggeshall, K. Mark
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3071148/
https://ncbi.nlm.nih.gov/pubmed/21357534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1004058
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