Bacillus anthracis peptidoglycan activates human platelets through FcγRII and complement

Platelet activation frequently accompanies sepsis and contributes to the sepsis-associated vascular leakage and coagulation dysfunction. Our previous work has implicated peptidoglycan (PGN) as an agent causing systemic inflammation in gram-positive sepsis. We used flow cytometry and fluorescent micr...

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Detalhes bibliográficos
Main Authors: Sun, Dawei, Popescu, Narcis I., Raisley, Brent, Keshari, Ravi S., Dale, George L., Lupu, Florea, Coggeshall, K. Mark
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2013
Assuntos:
Platelets and Thrombopoiesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3724192/
https://ncbi.nlm.nih.gov/pubmed/23733338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-02-486613
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