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Crosstalk between the coagulation and complement systems in sepsis

Sepsis is a potent activator of the hemostatic and complement systems. While local activation of these proteolytic cascades contributes to the host defense, their uncontrolled systemic activation has major tissue damaging effects that lead to multiple organ failure and death. We have extensively stu...

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Detalhes bibliográficos
Main Authors: Lupu, Florea, Keshari, Ravi S., Lambris, John D., Coggeshall, K. Mark
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4154483/
https://ncbi.nlm.nih.gov/pubmed/24759136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.thromres.2014.03.014
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