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Crosstalk between the coagulation and complement systems in sepsis

Sepsis is a potent activator of the hemostatic and complement systems. While local activation of these proteolytic cascades contributes to the host defense, their uncontrolled systemic activation has major tissue damaging effects that lead to multiple organ failure and death. We have extensively stu...

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Autori principali: Lupu, Florea, Keshari, Ravi S., Lambris, John D., Coggeshall, K. Mark
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4154483/
https://ncbi.nlm.nih.gov/pubmed/24759136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.thromres.2014.03.014
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