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A proteolytic pathway that controls the cholesterol content of membranes, cells, and blood

The integrity of cell membranes is maintained by a balance between the amount of cholesterol and the amounts of unsaturated and saturated fatty acids in phospholipids. This balance is maintained by membrane-bound transcription factors called sterol regulatory element-binding proteins (SREBPs) that a...

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Detalles Bibliográficos
Main Authors: Brown, Michael S., Goldstein, Joseph L.
Formato: Artigo
Idioma:Inglês
Publicado: The National Academy of Sciences 1999
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC34238/
https://ncbi.nlm.nih.gov/pubmed/10500120
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