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Steric Restrictions of RISC in RNA Interference Identified with Size-Expanded RNA Nucleobases
Understanding the interactions between small interfering RNAs (siRNAs) and the RNA-induced silencing complex (RISC) – the key protein complex of RNA interference (RNAi) – is of great importance to the development of siRNAs with improved biological, and potentially therapeutic, function. Although var...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3423588/ https://ncbi.nlm.nih.gov/pubmed/22646660 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb300174c |
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