N-octanoyl-Dopamine Is an Agonist at the Capsaicin Receptor TRPV1 and Mitigates Is Chemia-Induced Acute Kidney Injury in Rat

Since stimulation of transient receptor potential channels of the vanilloid receptor subtype 1 (TRPV1) mitigates acute kidney injury (AKI) and endogenous N-acyl dopamine derivatives are able to activate TRPV1, we tested if synthetic N-octanoyl-dopamine (NOD) activates TRPV1 and if it improves AKI. T...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Tsagogiorgas, Charalambos, Wedel, Johannes, Hottenrott, Maximilia, Schneider, Michael O., Binzen, Uta, Greffrath, Wolfgang, Treede, Rolf-Detlef, Theisinger, Bastian, Theisinger, Sonja, Waldherr, Rüdiger, Krämer, Bernhard K., Thiel, Manfred, Schnuelle, Peter, Yard, Benito A., Hoeger, Simone
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2012
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3423369/
https://ncbi.nlm.nih.gov/pubmed/22916273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043525
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky