The capsaicin receptor TRPV1 is the first line defense protecting from acute non damaging heat: a translational approach

BACKGROUND: Pain is the vital sense preventing tissue damage by harmful noxious stimuli. The capsaicin receptor TRPV1 is activated by noxious temperatures, however, acute heat pain is only marginally affected in mice after TRPV1 knockout but completely eliminated in mice lacking TRPV1 positive fiber...

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Bibliografiska uppgifter
I publikationen:J Transl Med
Huvudupphovsmän: Rosenberger, Daniela C., Binzen, Uta, Treede, Rolf-Detlef, Greffrath, Wolfgang
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2020
Ämnen:
Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6966804/
https://ncbi.nlm.nih.gov/pubmed/31952468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-019-02200-2
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