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The capsaicin receptor TRPV1 is the first line defense protecting from acute non damaging heat: a translational approach

BACKGROUND: Pain is the vital sense preventing tissue damage by harmful noxious stimuli. The capsaicin receptor TRPV1 is activated by noxious temperatures, however, acute heat pain is only marginally affected in mice after TRPV1 knockout but completely eliminated in mice lacking TRPV1 positive fiber...

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Publié dans:J Transl Med
Auteurs principaux: Rosenberger, Daniela C., Binzen, Uta, Treede, Rolf-Detlef, Greffrath, Wolfgang
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2020
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6966804/
https://ncbi.nlm.nih.gov/pubmed/31952468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-019-02200-2
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