N-Octanoyl dopamine transiently inhibits T cell proliferation via G1 cell-cycle arrest and inhibition of redox-dependent transcription factors

Recently, we developed a nonhemodynamic dopamine derivative, NOD, which has profound anti-inflammatory effects in vitro. As NOD also protects rats from ischemic AKI, the present study tested whether NOD is able to modulate cellular immunity for potential use as a T cell-suppressive agent. To this en...

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Dettagli Bibliografici
Pubblicato in:J Leukoc Biol
Autori principali: Wedel, Johannes, Hottenrott, Maximillia C., Stamellou, Eleni, Breedijk, Annette, Tsagogiorgas, Charalambos, Hillebrands, Jan-Luuk, Yard, Benito A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Leukocyte Biology 2014
Soggetti:
Inflammation, Extracellular Mediators, & Effector Molecules
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5395937/
https://ncbi.nlm.nih.gov/pubmed/24929005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.3A0813-455R
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