N-Octanoyl Dopamine Treatment of Endothelial Cells Induces the Unfolded Protein Response and Results in Hypometabolism and Tolerance to Hypothermia

AIM: N-acyl dopamines (NADD) are gaining attention in the field of inflammatory and neurological disorders. Due to their hydrophobicity, NADD may have access to the endoplasmic reticulum (ER). We therefore investigated if NADD induce the unfolded protein response (UPR) and if this in turn influences...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Stamellou, Eleni, Fontana, Johann, Wedel, Johannes, Ntasis, Emmanouil, Sticht, Carsten, Becker, Anja, Pallavi, Prama, Wolf, Kerstin, Krämer, Bernhard K., Hafner, Mathias, van Son, Willem J., Yard, Benito A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2014
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4057113/
https://ncbi.nlm.nih.gov/pubmed/24926788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0099298
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg