N-Octanoyl Dopamine Treatment of Endothelial Cells Induces the Unfolded Protein Response and Results in Hypometabolism and Tolerance to Hypothermia

AIM: N-acyl dopamines (NADD) are gaining attention in the field of inflammatory and neurological disorders. Due to their hydrophobicity, NADD may have access to the endoplasmic reticulum (ER). We therefore investigated if NADD induce the unfolded protein response (UPR) and if this in turn influences...

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Detalhes bibliográficos
Main Authors: Stamellou, Eleni, Fontana, Johann, Wedel, Johannes, Ntasis, Emmanouil, Sticht, Carsten, Becker, Anja, Pallavi, Prama, Wolf, Kerstin, Krämer, Bernhard K., Hafner, Mathias, van Son, Willem J., Yard, Benito A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4057113/
https://ncbi.nlm.nih.gov/pubmed/24926788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0099298
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