Aldose reductase modulates cardiac glycogen synthase kinase-3β phosphorylation during ischemia-reperfusion

Earlier studies have demonstrated that aldose reductase (AR) plays a key role in mediating ischemia-reperfusion (I/R) injury. Our objective was to investigate if AR mediates I/R injury by influencing phosphorylation of glycogen synthase kinase-3β (p-GSK3β). To investigate this issue, we used three s...

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Detalhes bibliográficos
Main Authors: Abdillahi, Mariane, Ananthakrishnan, Radha, Vedantham, Srinivasan, Shang, Linshan, Zhu, Zhengbin, Rosario, Rosa, Zirpoli, Hylde, Bohren, Kurt M., Gabbay, Kenneth H., Ramasamy, Ravichandran
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2012
Assuntos:
Energetics and Metabolism
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3423166/
https://ncbi.nlm.nih.gov/pubmed/22661511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00999.2011
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