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Human SLC2A9a and SLC2A9b isoforms mediate electrogenic transport of urate with different characteristics in the presence of hexoses

Human SLC2A9 (GLUT9) is a novel high-capacity urate transporter belonging to the facilitated glucose transporter family. In the present study, heterologous expression in Xenopus oocytes has allowed us to undertake an in-depth radiotracer flux and electrophysiological study of urate transport mediate...

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Detalhes bibliográficos
Main Authors: Witkowska, Kate, Smith, Kyla M., Yao, Sylvia Y. M., Ng, Amy M. L., O'Neill, Debbie, Karpinski, Edward, Young, James D., Cheeseman, Christopher I.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3423118/
https://ncbi.nlm.nih.gov/pubmed/22647630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00134.2012
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