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WHY IS DELTA ENDOCYTOSIS REQUIRED FOR EFFECTIVE ACTIVATION OF NOTCH?

A number of recent studies have shown that endocytosis of Notch ligands is required for activation of Notch. There are at least two broad models that account for how Delta endocytosis in one cell might contribute to activation of Notch in the neighboring cell. The first class of models is related to...

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Detalhes bibliográficos
Autor principal: Chitnis, Ajay
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3423086/
https://ncbi.nlm.nih.gov/pubmed/16425217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvdy.20683
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