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Interaction with Notch determines endocytosis of specific Delta ligands in zebrafish neural tissue

Mind bomb1 (Mib1)-mediated endocytosis of the Notch ligand DeltaD is essential for activation of Notch in a neighboring cell. Although most DeltaD is localized in cytoplasmic puncta in zebrafish neural tissue, it is on the plasma membrane in mib1 mutants because Mib1-mediated endocytosis determines...

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Detalhes bibliográficos
Main Authors: Matsuda, Miho, Chitnis, Ajay B.
Formato: Artigo
Idioma:Inglês
Publicado em: Company of Biologists 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2685967/
https://ncbi.nlm.nih.gov/pubmed/19056830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.027938
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