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Identification of the Mind Bomb1 Interaction Domain in Zebrafish DeltaD

Ubiquitylation promotes endocytosis of the Notch ligands like Delta and Serrate and is essential for them to effectively activate Notch in a neighboring cell. The RING E3 ligase Mind bomb1 (Mib1) ubiquitylates DeltaD to facilitate Notch signaling in zebrafish. We have identified a domain in the intr...

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Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Palardy, Gregory, Chitnis, Ajay B.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4447371/
https://ncbi.nlm.nih.gov/pubmed/26020642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0127864
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